Mechanical properties of nanoparticles in the drug delivery kinetics

Nanoparticle formulation is a recently developed drug delivery technology with enhanced targeting potential. Nanoparticles encapsulate the of choice and delivers it to target via molecules (ex. antigen) located on nanoparticle surface. can even be targeted deeply penetrating tissue modeled deliver drugs through blood brain barrier. These advancements are providing better disease such as cancer Alzheimer’s. Various polymers manufactured into nanoparticles. The examined in this paper polycaprolactone (PCL), poly(lactic acid) (PLA), poly(lactic-co-glycolic (PLGA), poly(glycolic (PGA). purpose study analyze mechanical properties these establish trends model pharmacokinetics biotransport. We found that, general, melting point, elastic modulus tensile strength increases, degradation rate also increases. PLA composite material may an ideal polymer for due its good control degradation.